Cast

Jamie Foxx as Nathaniel Ayers.
Robert Downey Jr. as Steve Lopez.
Catherine Keener as Mary Weston (formerly Mary Lopez).
Tom Hollander as Graham Claydon.
Lisa Gay Hamilton as Jennifer.
Rachael Harris as Lopez's co-worker.
Jena Malone as a lab technician.
Diana Gomes as a Psychologist.
Stephen Root as Curt Reynolds.
Marcus Carl Franklin as Young Nathaniel Ayers.
Lorraine Toussaint as Flo Ayers.